Highly regioselective synthesis of 1,3-diiodonaphthalene derivatives via a sequential cascade iodocyclization |
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| Authors: | Wang Li-Jing Zhu Hai-Tao Lu Lei Yang Fang Liu Xue-Yuan Liang Yong-Min |
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| Institution: | State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou Institute of Chemical Physics, Chinese Academy of Science, Lanzhou 730000, PR China. |
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| Abstract: | A novel and flexible sequentially cascade iodocyclization for the synthesis of highly substituted 1,3-diiodinated naphthalene derivatives in up to 99% yield under mild conditions is reported. The dihalogenated moiety can be readily introduced into the naphthalenes in a position that is usually not easily functionalized. |
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