Abstract: | All four possible isomers of 4-ureido-3-hydroxy-2-(5 -alkoxycarbonylbutyl)-thiophan were synthesized by the action of potassium isocyanate on the corresponding hydrochlorides (or hydrobromides) of the stereoisomers of A-amino-3-hydroxy-2[5 -methoxy (or ethoxy)carbonylbutyl]thiophans, which were obtained by several methods. The configurations of the compounds obtained were proved by PMR spectroscopy.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 616–620, May, 1980 |