Stereoselective synthesis of fluorinated 1,3-cis-diaminocyclopentanes |
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Authors: | Pasco Morgane Moumné Roba Lecourt Thomas Micouin Laurent |
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Affiliation: | UMR8638, CNRS-Paris Descartes University, Laboratoire de Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques, 4 av. de l'Observatoire, 75006 Paris, France. |
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Abstract: | Several fluorinated 1,3-diaminocyclopentanes, previously reported to be useful RNA structural probes, can be prepared in a diastereoselective manner from a single bicyclic hydrazine precursor, in 3 to 9 steps. |
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