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Stereoselective synthesis of fluorinated 1,3-cis-diaminocyclopentanes
Authors:Pasco Morgane  Moumné Roba  Lecourt Thomas  Micouin Laurent
Affiliation:UMR8638, CNRS-Paris Descartes University, Laboratoire de Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques, 4 av. de l'Observatoire, 75006 Paris, France.
Abstract:Several fluorinated 1,3-diaminocyclopentanes, previously reported to be useful RNA structural probes, can be prepared in a diastereoselective manner from a single bicyclic hydrazine precursor, in 3 to 9 steps.
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