| 蛋白质组学中基质辅助激光解吸电离的基质研究进展 |
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| 引用本文： | 许亚伟,陆豪杰,杨芃原.蛋白质组学中基质辅助激光解吸电离的基质研究进展[J].分析化学,2007,35(3):455-460. |
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| 作者姓名： | 许亚伟 陆豪杰 杨芃原 |
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| 作者单位： | 复旦大学化学系,上海,200433;复旦大学生物医学研究院,上海,200032 |
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| 基金项目： | 国家自然科学基金
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上海市重点基础研究项目
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上海市青年科技启明星计划(A类) |
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| 摘 要： | 基质辅助激光解吸电离(MALDI)技术是近年来发展起来的新的质谱离子化技术。本文较为系统地综述了应用于蛋白质组学中的MALDI基质的最新进展以及不同的基质的优缺点及应用范围,并且归纳了其发展趋势。
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| 关 键 词： | 基质辅助激光解吸电离 质谱 基质 蛋白质 多肽 评述 |
| 修稿时间： | 2006-05-222006-08-14 |
Recent Development of Matrix Assisted Laser Desorption Ionization Matrix Applied in Proteomics |
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| Xu Ya-Wei,Lu Hao-Jie,Yang Peng-Yuan.Recent Development of Matrix Assisted Laser Desorption Ionization Matrix Applied in Proteomics[J].Chinese Journal of Analytical Chemistry,2007,35(3):455-460. |
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| Authors: | Xu Ya-Wei Lu Hao-Jie Yang Peng-Yuan |
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| Institution: | 1.Department of Chemistry, Fudan University, Shanghai 200433; 2. Institutes of Biomedical Sciences, Fudan University, Shanghai 200032 |
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| Abstract: | Matrix assisted laser desorption ionization (MALDI) technology is one of the best mass spectrometry ionization technologies for macro molecules which was developed almost two decades ago. From organic compounds to inorganic materials, there are a lot of matrices that have been developed for MALDI. In this article, we conclude the recent development of MALDI matrix applied in proteomics and discuss its prospect. |
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| Keywords: | Matrix assisted laser desorption ionization mass spectrometry matrix protein peptide review |
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