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薯蔓总黄酮的免疫调节作用
引用本文:罗丽萍,高荫榆,熊绍员,洪雪娥,夏冬华. 薯蔓总黄酮的免疫调节作用[J]. 南昌大学学报(理科版), 2006, 30(5): 489-491
作者姓名:罗丽萍  高荫榆  熊绍员  洪雪娥  夏冬华
作者单位:南昌大学,食品科学教育部重点实验室,江西,南昌,330031;江西省植保植检总站,江西,南昌,330046
基金项目:江西省科技厅农业重大基金
摘    要:研究薯蔓总黄酮(FSPV)的非特异性免疫和特异性体液免疫调节作用。采用碳粒廓清实验研究了FSPV对正常和免疫低下小鼠的非特异性免疫功能;血清溶血素测定法研究了FSPV的特异性体液免疫功能。FSPV可提高正常和免疫低下小鼠的廓清指数K和吞噬指数a,尤其是400mg/kg剂量可使廓清指数极显著升高(P〈0.01);实验所用剂量的FSPV对小鼠的血清溶血素HC50无显著影响。FSPV具有促进单核巨噬细胞系统吞噬功能的作用,可增强小鼠的非特异性免疫功能,但对小鼠的特异性体液免疫功能无显著影响。

关 键 词:薯蔓  黄酮类化合物  免疫调节作用  非特异性免疫  特异性体液免疫
文章编号:1006-0464(2006)05-0489-03
收稿时间:2005-12-08
修稿时间:2005-12-08

The Study of Immunoregulation Effect of FSPV
LUO Li-ping,GAO Yin-yu,XIONG Shao-yuan,HONG Xue-e,XIA Dong-hua. The Study of Immunoregulation Effect of FSPV[J]. Journal of Nanchang University(Natural Science), 2006, 30(5): 489-491
Authors:LUO Li-ping  GAO Yin-yu  XIONG Shao-yuan  HONG Xue-e  XIA Dong-hua
Affiliation:1. The Key Laboratory of Food Science of MOE, Nanchang Ubiversity, Nanchang,330047, China ; 2. Plant Protection Station of Jiangxi Province, Nanchang 330046, China
Abstract:To investigate the immunoregulation effect of FSPV.By using carbon particle clearance test to study the nonspecific immunological function of FPSV on normal and immunosuppression mice.By using the hemolysin test to study the specific humoral immunological effect of FSPV on normal mice.The carbon particle clearance index and phagocytic index of normal and immunosuppression mice is increased by giving FSPV to the mice.Especially when the dose is 400mg/kg,the carbon particle clearance is increased remarkably(P<0.01).FSPV has no significant influence on HC_(50).FSPV has potent enhancement on non-specific immunity of mice.But it has no remarkable influence on the humoral immunity.
Keywords:sweet potato vine    flavonoid    immunoregulation    non - specific immunity    humoral immunity
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