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A concise and stereoselective synthesis of (+)- and (−)-deoxoprosophylline
Authors:Subhash P Chavan  Cherukupally Praveen
Institution:Division of Organic Chemistry: Technology, National Chemical Laboratory, Pashan, Pune 411 008, India
Abstract:An efficient synthesis of (+)- and (−)-deoxoprosophylline was accomplished from the readily available cis-2-butene-1,4-diol in which the Sharpless asymmetric dihydroxylation was used as the key step.
Keywords:deoxoprosophylline  Claisen rearrangement  Sharpless asymmetric dihydroxylation  piperidine alkaloids
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