Selective α-monoallylation of phenyl ketones and benzocycloalkanones under microwave irradiation |
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| Authors: | José M. Cid |
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| Affiliation: | Johnson and Johnson Pharmaceutical Research and Development, a Division of Janssen-Cilag S.A., Jarama s/n, 45007 Toledo, Spain |
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| Abstract: | A method for the selective α-monoallylation of phenyl ketones and benzocycloalkanones with allyl alcohol under microwave irradation is described. The corresponding α-allyl ketones are obtained in moderate to good yields with only minor quantities of diallylation by-products. |
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| Keywords: | Microwave assisted synthesis Monoallylation Benzocycloalkanones Phenyl ketones |
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