A novel methodology for the synthesis of 1-desoxy-Δ-tetrahydrocannabinol (THC) analogues |
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Authors: | Hang Sun |
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Affiliation: | Organix, Inc., 240 Salem Street, Woburn, MA 01801, USA |
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Abstract: | A versatile and efficient sequence was developed for the synthesis of 1-desoxy-Δ8-THC analogues and is demonstrated by the synthesis of sulfonamide analogues with an acetylene group at the C-2′ position in the side chain. In this procedure the 1-desoxy-Δ8- THC ring structure is built first and the synthesis of the side chain is then developed. |
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Keywords: | Cannabinoids Synthesis 1-Desoxy-THC analogues |
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