A facile total synthesis of rutaecarpine |
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| Authors: | Subhash P Chavan R Sivappa |
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| Institution: | Division of Organic Chemistry: Technology, National Chemical Laboratory, Pune 411-008, India |
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| Abstract: | The indoloquinazoline alkaloid rutaecarpine has been synthesized efficiently by employing 9,10,11,12-tetrahydro-4H-pyrido2,1-b]quinazoline-4,9-dione (4) as a key intermediate, which was prepared by adapting a Dieckmann condensation-decarboxylation sequence from quinazolinone diester 6. |
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| Keywords: | Rutaecarpine Indoloquinazoline alkaloid Dieckmann condensation-decarboxylation |
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