A novel synthesis of spiro[(2,2-dimethyl-[1,3]-dioxane)-5,2′-(2′,3′-dihydroindole)] using SRN1 reaction conditions |
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Authors: | I Sánchez |
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Abstract: | A concise synthesis of the spiro(2,2-dimethyl-1,3]-dioxane)-5,2′-(2′,3′-dihydroindole)] nucleus from substituted benzyl chlorides and 5-(hydroxymethyl)-2,2-dimethyl-5-nitro-1,3-dioxane 5 as starting materials is reported. The nitro intermediates 6 and 7 were prepared under SRN1 reaction conditions. |
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Keywords: | Spiroindolines Cyclization SRN1 reaction conditions 1 3-Dioxane Nitronate anion |
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