P-stereogenic P/N hybrid ligands: a remarkable switch in enantioselectivity in palladium-catalyzed asymmetric allylation |
| |
| Authors: | Hiroshi Danjo |
| |
| Affiliation: | Department of Chemistry, Faculty of Science, Chiba University, Yayoi-cho, Inage-ku, Chiba 263-8522, Japan |
| |
| Abstract: | Optically active P-stereogenic phosphine/oxazoline bidentate ligands (1) were prepared and applied to palladium-catalyzed allylic substitution of 1,3-diphenyl-1-acetoxy-2-propene with dimethyl malonate. The absolute configuration of the allylation product was remarkably switched by changing a palladium/ligand ratio between 1/1 and 1/2. |
| |
| Keywords: | Palladium Asymmetric allylic substitution P-stereogenic phosphine P/N hybrid ligand |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
