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Copper-mediated coupling of aminopurines and aminopyrimidines with arylboronic acids
Authors:Ramesh A. Joshi
Affiliation:Division of Organic Chemistry Technology, National Chemical Laboratory, Dr. Homibhabha Road, Pune 411 008, India
Abstract:Selective N-arylation of aminopurines and aminopyrimidines 1-3 with arylboronic acids 4-6 was explored using copper(II) acetate and the corresponding N-arylated purine and pyrimidine derivatives 7-15 were obtained in moderate to good yields.
Keywords:N-arylation   arylboronic acid   aminopurine   aminopyrimidine   copper(II) acetate
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