New synthesis of benzo[b]furan and indole derivatives from 1,1-dibromo-1-alkenes using a tandem Pd-assisted cyclization-coupling reaction |
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| Authors: | Sabine Thielges Jacques Eustache |
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| Affiliation: | Laboratoire de Chimie Organique et Bioorganique associé au CNRS, Université de Haute-Alsace, Ecole Nationale Supérieure de Chimie de Mulhouse 3, rue Alfred Werner, F-68093 Mulhouse Cedex, France |
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| Abstract: | We report a new flexible method for the synthesis of 2-functionalized benzo[b]furans and indoles from readily available o-(2,2-dibromovinyl)-phenol, -aniline or -acetanilide using a tandem Pd-assisted cyclization-coupling reaction. |
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| Keywords: | Benzofuran Indole Palladium chemistry Tandem reaction Dibromo-alkenes |
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