A novel and direct synthesis of chroman derivatives using a hypervalent iodine(III) reagent |
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Authors: | Hiromi Hamamoto |
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Affiliation: | Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, Japan |
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Abstract: | The direct aromatic carbon-oxygen bond-formation reaction was described and the novel and simple synthetic method for chroman derivatives involving aromatic cation radical intermediates was developed using the hypervalent iodine(III) reagent, phenyliodine(III) bis(trifluoroacetate) (PIFA). |
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Keywords: | Chromans Cyclization Hypervalent iodine reagents Heterocycles Oxidation |
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