Regioselective oxidation of N-alkylpyrrolidines to pyrrolidin-5-ones by RuCl3/NaIO4 |
| |
| Authors: | Nagendra K Sharma |
| |
| Institution: | Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pashan Road, Pune 411008, India |
| |
| Abstract: | RuCl3/NaIO4 under EtOAc/H2O biphasic conditions, selectively oxidizes the Nα-endo-methylene group of pyrrolidine derivatives, without affecting the exo-methylene group adjacent to the N-heteroatom. |
| |
| Keywords: | RuCl3/NaIO4 Oxidation N-Alkyl pyrrolidinones |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
