Aziridination of alkenes with N-substituted hydrazines mediated by iodobenzene diacetate |
| |
| Authors: | Jiayin Li Philip Wai Hong Chan |
| |
| Institution: | a Shanghai-Hong Kong Joint Laboratory on Chemical Synthesis, Shanghai Institute of Organic Synthesis, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, PR China
b Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, PR China |
| |
| Abstract: | Aziridination of a variety of alkenes with N-substituted hydrazines mediated by iodobenzene diacetate under mild conditions (K2CO3, CH2Cl2) and ambient temperature were achieved in good to excellent yields (up to 99%), and conversions. The practicality and simplicity of this C-N bond formation protocol was exemplified by its application to the aziridination of cholesteryl acetate in a stereoselective manner. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
