Concise total synthesis of (+)-carpamic acid |
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Authors: | Stefan Randl |
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Institution: | Technische Universität Berlin, Institut für Chemie, Strasse des 17. Juni 135, D-10623 Berlin, Germany |
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Abstract: | We report herein an efficient enantioselective synthesis of (+)-carpamic acid, with nine steps as the longest linear sequence, the key strategy being based on a novel sequence of a cross-metathesis (CM) reaction and a subsequent cyclizing reductive amination to form the piperidine ring. |
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