Iodine/MeOH: a novel and efficient reagent system for thiocyanation of aromatics and heteroaromatics |
| |
Authors: | JS Yadav BVS Reddy S Shubashree K Sadashiv |
| |
Institution: | Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500007, India |
| |
Abstract: | Indoles, pyrroles, oxindoles and aromatic amino compounds undergo smooth thiocyanation with ammonium thiocyanate in the presence of molecular iodine in methanol under mild conditions to afford the corresponding 3-indolyl, 2-pyrrolyl and 4-aryl thiocyanates, respectively, in excellent yields with high selectivity. The reactions proceed rapidly at room temperature without heating or the use of strong Lewis acids. |
| |
Keywords: | Thiocyanation Aromatic systems Iodine catalysis Aryl thiocyanates |
本文献已被 ScienceDirect 等数据库收录! |