Syntheses of two cytotoxic polyunsaturated pyrrole metabolites of the marine sponge Mycale micracanthoxea |
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| Authors: | Trond Vidar Hansen,Lars Skattebø l |
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| Affiliation: | a School of Pharmacy, Department of Medicinal Chemistry, University of Oslo, PO Box 1185, Blindern, N-0316, Oslo, Norway
b Department of Chemistry, University of Oslo, PO Box 1033, Blindern, N-0315, Oslo, Norway |
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| Abstract: | Starting from eicosapentaenoic acid (EPA) the marine, naturally occurring, pyrrole derivatives, mycalazol 5 and mycalazal 2 have been synthesized. The Stille coupling reaction is a key step in the syntheses. |
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| Keywords: | Pyrroles Synthesis Stille coupling |
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