Synthesis of hydroxylated hexahydropyrrolo[2,1-b]thiazoles |
| |
Authors: | Karoly Agoston |
| |
Institution: | Department of Organic Chemistry, University of Regensburg, Unistr 31, Regensburg D-93040, Germany |
| |
Abstract: | An unexpected ring contraction of 7,5-fused bicyclic thiazolidinelactams yields hexahydropyrrolo2,1-b]thiazoles in a single synthetic step. Three stereocentres are inverted along the highly stereoselective reaction path. The title compounds are further transformed into thio-analogues of polyhydroxylated pyrrolizidine alkaloids. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|