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Short and efficient chemoenzymatic synthesis of goniothalamin
Authors:Michelangelo Gruttadauria  Paolo Lo Meo  Renato Noto
Affiliation:Dipartimento di Chimica Organica ‘E. Paternò’, Università di Palermo, Viale delle Scienze, Parco d’Orleans II, 90128 Palermo, Italy
Abstract:A high-yielding three-step synthesis of goniothalamin involving an enzymatic kinetic resolution in the presence of vinyl acrylate followed by ring-closing metathesis is discussed.
Keywords:lipase   δ-lactones   goniothalamin
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