Short and efficient chemoenzymatic synthesis of goniothalamin |
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Authors: | Michelangelo Gruttadauria Paolo Lo Meo Renato Noto |
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Affiliation: | Dipartimento di Chimica Organica ‘E. Paternò’, Università di Palermo, Viale delle Scienze, Parco d’Orleans II, 90128 Palermo, Italy |
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Abstract: | A high-yielding three-step synthesis of goniothalamin involving an enzymatic kinetic resolution in the presence of vinyl acrylate followed by ring-closing metathesis is discussed. |
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Keywords: | lipase δ-lactones goniothalamin |
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