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A convenient synthesis of dihydro- and tetrahydro-1,3-thiazine derivatives from β-aryl-β-amino acids
Authors:Nicolas Leflemme  Sylvain Rault
Affiliation:Centre d’Etudes et de Recherche sur le Médicament de Normandie, UFR des Sciences Pharmaceutiques, 1 rue Vaubénard 14032 CAEN cedex, France
Abstract:A facile synthesis of 2-alkyl-4-aryl-5,6-dihydro-4H-1,3-thiazines and cis-2-alkyl-4-aryl-3,4,5,6-tetrahydro-2H-1,3-thiazines with potential therapeutic interest was achieved starting from readily accessible β-aryl-β-amino acids.
Keywords:5,6-Dihydro-4H-1,3-thiazines   3,4,5,6-Tetrahydro-2H-1,3-thiazines   β-Aryl-β-amino acids
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