A convenient synthesis of dihydro- and tetrahydro-1,3-thiazine derivatives from β-aryl-β-amino acids |
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Authors: | Nicolas Leflemme Sylvain Rault |
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Affiliation: | Centre d’Etudes et de Recherche sur le Médicament de Normandie, UFR des Sciences Pharmaceutiques, 1 rue Vaubénard 14032 CAEN cedex, France |
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Abstract: | A facile synthesis of 2-alkyl-4-aryl-5,6-dihydro-4H-1,3-thiazines and cis-2-alkyl-4-aryl-3,4,5,6-tetrahydro-2H-1,3-thiazines with potential therapeutic interest was achieved starting from readily accessible β-aryl-β-amino acids. |
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Keywords: | 5,6-Dihydro-4H-1,3-thiazines 3,4,5,6-Tetrahydro-2H-1,3-thiazines β-Aryl-β-amino acids |
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