Stereocontrolled addition of boron enolates to trans α,β-aziridine aldehydes. A new route to anti-1,2-amino alcohols |
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| Authors: | Giuliana Righi Simona Ciambrone |
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| Institution: | Istituto di Chimica Biomolecolare-Sezione di Roma, c/o Dipartimento di Chimica, Università ‘La Sapienza’, P.le A. Moro 5, 00185 Roma, Italy |
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| Abstract: | A study of the addition of boron enolates of methyl ketones to trans α,β-aziridine aldehydes is reported. The reaction proceeds with excellent anti stereoselectivity furnishing functionalized products, capable of other controlled transformations, some of which are described. |
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| Keywords: | α β-Aziridine aldehydes Boron enolates Aldol condensation 1 2-Amino alcohols |
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