A Diels-Alder approach for the synthesis of highly functionalized benzo-annulated indane-based α-amino acid derivatives via a sultine intermediate

The synthesis of various highly functionalized benzo-annulated indane-based α-amino acid (AAA) derivatives are reported via a 4+2] cycloaddition strategy using a sultine derivative, containing an AAA moiety, as a reactive diene component. By adopting this strategy, a new α,α-dialkylated indane-based C₆₀ fullerene containing a constrained AAA unit is reported.