Deuteration of α,β-acetylenic esters, amides, or carboxylic acids without using deuterium gas: synthesis of 2,2,3,3-tetradeuterioesters, amides, or acids |
| |
Abstract: | An easy, simple, rapid, and nonhazardous deuteration of the C-C triple bond of α,β-acetylenic esters, amides, or acids by means of samarium diiodide in the presence of D2O, provides an efficient method for synthesizing 2,2,3,3-tetradeuterioesters, amides, or carboxylic acids, respectively. When H2O is used instead of D2O, saturated carboxylic esters, amides, or acids were isolated. A mechanism to explain these reduction reactions has been proposed. |
| |
Keywords: | Deuterium Reductions Samarium diiodide |
本文献已被 ScienceDirect 等数据库收录! |
|