Carvone epoxidation by system “hydrogen peroxide-[Mn2L2O3][PF6]2 (L = 1,4,7-trimethyl-1,4,7-triazacyclononane)-carboxylic acid”: a combinatorial approach to the process optimization? |
| |
Authors: | Dalmo Mandelli Rafael A. Steffen Georgiy B. Shul''pin |
| |
Affiliation: | (1) Pontifícia Universidade Católica de Campinas, Faculdade de Química, Campus I, Rod. D. Pedro I, km 136, Pq. das Universidades, Campinas, SP, 13086-900, Brazil;(2) Pontifícia Universidade Católica de Campinas, Faculdade de Química, Campus I, Rod. D. Pedro I, km 136, Pq. das Universidades, Campinas, SP, 13086-900, Brazil;(3) Semenov Institute of Chemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow 119991, Russia |
| |
Abstract: | Summary Epoxidation of natural terpene (+)-carvone by the system consisting of a catalyst, oxalic acid (co-catalyst) and H2O2 (70% aqueous solution; oxidant) was studied and factorial design methods were applied for the optimization of this reaction. A dinuclear manganese(IV) complex [LMn(O)3MnL](PF6)2 (L = 1,4,7-trimethyl-1,4,7-triazacyclononane) was used as a catalyst, and acetonitrile was employed as a solvent. An analysis by methods of the complete 24 factorial design showed that an increase in the catalyst concentration gives a strong positive effect on the carvone conversion and selectivity. Hydrogen peroxide has a smaller positive effect on the conversion, but at high concentration, H2O2 leads to some decrease in the selectivity. An increase in the oxalic acid concentration has a beneficial effect on the conversion, but does not affect the selectivity. |
| |
Keywords: | hydrogen peroxide optimization Epoxidation manganese complexes homogeneous catalysis |
本文献已被 SpringerLink 等数据库收录! |
|