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One-pot-synthesis of novel cinchonine-based phosphites
Authors:Qiao Feng Wang  Xue Ying Liu  Xiang Yang Qin  Xiao Ye Li  Sheng Yong Zhang
Institution:Department of Chemistry, Fourth Military Medical University, Xi'an 710032, China
Abstract:Cinchonine was employed as backbone for the synthesis of novel phosphite compounds with diol substituents.These monophosphinites were provided in one pot with the yields ranged from 63%to 75%.Their structures were confirmed by NMR spectroscopy and HRMS.
Keywords:Cinchona alkaloids  Diols  Chiral phosphite  Asymmetric reaction  Ligand
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