A new and concise synthetic route to an enantiopure (+)-conduritol-E derivative from diethyl l-tartrate期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

A new and concise synthetic route to an enantiopure (+)-conduritol-E derivative from diethyl l-tartrate

Affiliation:	1. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China;2. State Key Laboratory of Drug Research, and Natural Products Chemistry Department, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhangjiang Hi-Tech Park, Shanghai 201203, China;1. Department of Chemistry and Education Center for Basic Chemistry Experiments, Nanchang University, Nanchang 330031, China;2. Jiangxi Key Laboratory of Functional Organic Molecules, Jiangxi Normal University of Science & Technology, Nanchang 330013, China;1. School of Science, Beijing University of Chemical Technology, Beijing 100029, PR China;2. Interdisciplinary Research Centre in Biomedical Materials, COMSATS Institute of Information Technology, Lahore 54000, Pakistan

Abstract:	(+)-(1R,2R,3S,6S)-3,6-Di-O-methyl conduritol-E was efficiently synthesized in enantiomerically pure form starting from diethyl l-tartrate in 33% total yield using a ring-closing olefin metathesis reaction as one of the key steps.

Keywords:
本文献已被 ScienceDirect 等数据库收录！