A practical stereoselective synthesis of (2R,3S)-alloisoleucine |
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Affiliation: | Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323, USA |
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Abstract: | An efficient asymmetric Strecker synthesis of the unnatural α-amino acid, d-alloisoleucine (3), from commercially available and inexpensive (S)-2-methyl-1-butanol (4) was accomplished in four steps. |
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