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A practical stereoselective synthesis of (2R,3S)-alloisoleucine
Institution:Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323, USA
Abstract:An efficient asymmetric Strecker synthesis of the unnatural α-amino acid, d-alloisoleucine (3), from commercially available and inexpensive (S)-2-methyl-1-butanol (4) was accomplished in four steps.
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