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An unusual conformational similarity of two peptide folds featuring sulfonamide and carboxamide on the backbone
Authors:Kuruppanthara N Vijayadas  Hilda C Davis  Amol S Kotmale  Rupesh L Gawade  Vedavadi G Puranik  Pattuparambil R Rajamohanan  Gangadhar J Sanjayan
Affiliation:Division of Organic Synthesis, National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411 008, India. gj.sanjayan@ncl.res.in.
Abstract:Two folded peptides featuring carboxamide and sulfonamide at the core of the peptide fold have been shown to possess almost similar conformational features, despite the well-known fact that carboxamides and sulfonamides have strikingly different hydrogen-bonding and geometrical preferences.
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