A nanoscale graphene oxide-peptide biosensor for real-time specific biomarker detection on the cell surface |
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Authors: | Zhe Wang Peng Huang Ashwinkumar Bhirde Albert Jin Ying Ma Gang Niu Nouri Neamati Xiaoyuan Chen |
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Affiliation: | Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China361005. |
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Abstract: | A nanoscale RGD-pyrene-graphene oxide (GO) biosensor was prepared for real-time in situ detection of a cancer cell surface marker, integrin αvβ3. This nanoscale GO-based biosensor is simple, robust, sensitive and of high selectivity. It can also be adapted to other cancer cell surface marker evaluation systems. |
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