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Macromolecular effects upon enzymatic degradation of chitosan in solution
Authors:E. I. Kulish  V. P. Volodina  R. R. Fatkullina  S. V. Kolesov  G. E. Zaikov
Affiliation:1. Bashkortostan State University, ul. Frunze 32, Ufa, 450074, Bashkortostan, Russia
2. Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, 450054, Bashkortostan, Russia
3. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119991, Russia
Abstract:Macromolecular effects were revealed in the course of enzymatic degradation of chitosan in an acetic acid solution under the action of hyaluronidase, a nonspecific enzyme. It was shown that the concentration of chitosan in the initial solution determines its supramolecular organization and, hence, the degree of enzymatic degradation.
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