|
|||||
|
|
Supramolecular self-assembly and controllable drug release of thermosensitive hyperbranched multiarm copolymers |
|
| Authors: | GUO Bo SUN XiaoYi ZHOU YongFeng & YAN DeYue College of Chemistry Chemical Engineering Shanghai Jiao Tong University Shanghai China |
| Institution: | GUO Bo,SUN XiaoYi,ZHOU YongFeng & YAN DeYue College of Chemistry , Chemical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China |
| Abstract: | A novel temperature-responsive hyperbranched multiarm copolymer with a hydrophobic hyperbranched poly(3-ethyl-3-(hydroxymethyl)oxetane)(HBPO) core and thermosensitive poly(N-isopropylacrylamide)(PNIPAM) arms was synthesized via the atom transfer radical polymerization(ATRP) of NIPAM monomers from a hyperbranched HBPO macroinitiator.It was found that HBPO-star-PNIPAM self-assembled into multimolecular micelles(around 60 nm) in water at room temperature according to pyrene probe fluorescence spectrometry,1H N... |
| Keywords: | hyperbranched polymers thermosensitive copolymer supramolecular self-assembly ATRP drug delivery |
| 本文献已被 CNKI 等数据库收录！ | |