One-pot synthesis of oxygen and nitrogen-bridged calix[2]arene[2]triazines |
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| Authors: | Xu-Dong Wang Zhi-Tang Huang Mei-Xiang Wang |
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| Affiliation: | 1. Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P.R. China;2. Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, P.R. China |
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| Abstract: | A simple and powerful one-pot reaction method was developed for the synthesis of heteracalixaromatics. In the presence of a base, one-pot macrocyclic condensation reaction between cyanuric chloride and 1,3-phenylene diols and diamines proceeded effectively under very mild conditions to afford a number of functionalised oxygen and nitrogen-bridged calix[2]arene[2]triazines in 33–54% yields. The method was applied in a multigram-scale (14.4 g) preparation of tetraoxacalix[2]arene[2]triazine. |
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| Keywords: | heteracalixaromatics calix[2]arene[2]triazine one-pot synthesis |
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