Regulation of alpha-chymotrypsin activity on the surface of substrate-functionalized gold nanoparticles |
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Authors: | You Chang-Cheng Arvizo Rochelle R Rotello Vincent M |
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Affiliation: | Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA. |
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Abstract: | A gold nanoparticle functionalized with substrates for alpha-chymotrypsin was fabricated to afford an enzyme modulator that exhibited enzyme-specific activation coupled with general inhibition of other proteases. |
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