Preparative synthesis of 2-[3-alkoxy-4-(hydroxy,alkoxy, acyloxy)phenyl]-1H-benzimidazoles proceeding from substituted benzaldehydes |
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| Authors: | Dikusar E. A. Potkin V. I. |
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| Affiliation: | 1.Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, Minsk, 220072, Belarus
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| Abstract: | New functionally-substituted 2-[3-alkoxy-4-(hydroxy, alkoxy, acyloxy)phenyl]-1H-benzimidazoles were synthesized in preparative yields from aldehydes of vanillin series, their ethers and esters by the reaction with 1,2-phenylenediamine in the presence of sodium hydrogen sulfite in DMF solution at 80°C. |
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