Intermolecular association of Tilan with vinylpyrrolidone copolymers |
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Authors: | D N Valeeva F Yu Akhmadullina V F Kurenkov D G Pobedimskii |
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Institution: | (1) Kazan State Technological University, Kazan, Tatarstan, Russia;(2) Moscow State Academy of Fine Chemical Technology, Moscow, Russia |
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Abstract: | The results of physicochemical studies of promising prolonging agents for Tilan antibiotic: polyvinylpyrrolidone and vinylpyrrolidone copolymers, are reported. The optimal component ratios of the drug formulation were determined by viscometry and conductometric titration. As determined by IR spectroscopy, the components are associated mainly via intermolecular hydrogen bonds. |
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