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Convenient synthesis of trifluoromethylated 2-pyrrolidone and 2-pyrrolone derivatives |
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| Authors: | Dmitriy A. Sibgatulin Dmitriy M. Volochnyuk Eduard B. Rusanov Alexander N. Chernega |
| Affiliation: | Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanska 5, Kyiv 02094, Ukraine |
| Abstract: | The reaction of a set of enamines with methyl trifluoropyruvate and its imine was investigated. As a result, a simple procedure for synthesis of trifluoromethylated 2-pyrrolidone and 2-pyrrolone derivatives has been developed. |
| Keywords: | Trifluoromethyl Methyl trifluoropyruvate Enamines Cyclization |
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