Piperazic acid-containing natural products: isolation, biological relevance and total synthesis |
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Authors: | Oelke Alexander J France David J Hofmann Tatjana Wuitschik Georg Ley Steven V |
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Affiliation: | Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. |
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Abstract: | Since their first discovery in 1959, natural products containing the piperazic acid motif have been isolated from a variety of sources and exhibit diverse biological activity profiles. This review provides information about their isolation and biological activities, and presents an overview of recent total syntheses of these molecules. |
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