Cascade dearomatization of N-substituted tryptophols via Lewis acid-catalyzed Michael reactions |
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| Authors: | Chuan Liu Wei Zhang Li-Xin Dai Shu-Li You |
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| Affiliation: | State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, P.R. China. slyou@sioc.ac.cn. |
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| Abstract: | Lewis acid-catalyzed cascade dearomatization of N-substituted tryptophols via Michael addition reaction was developed. The generality of the method has been demonstrated by the synthesis of versatile furoindoline derivatives with a quaternary carbon center in good yields. |
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