| 壳聚糖多孔支架电化学辅助沉积羟基磷灰石涂层研究 |
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| 引用本文： | 黄志海,李纪宏,林萍华,董寅生,郭超,盛晓波,储成林.壳聚糖多孔支架电化学辅助沉积羟基磷灰石涂层研究[J].高分子学报,2009,0(3):273-277. |
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| 作者姓名： | 黄志海 李纪宏 林萍华 董寅生 郭超 盛晓波 储成林 |
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| 作者单位： | 1. 东南大学,材料科学与工程学院,南京,211189
2. 东南大学,材料科学与工程学院,南京,211189;河海大学,材料科学与工程学院,南京,210098 |
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| 基金项目： | 江苏省高新技术研究项目，江苏省高等学校研究生创新计划项目 |
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| 摘 要： | 采用电化学辅助技术控制阴、阳两极溶液中的钙、磷离子定向迁移,进入壳聚糖多孔支架内部发生反应并在孔隙表面沉积,制备了有机-无机复合多孔支架.应用XRD、SEM、煅烧法、孔隙率测定和压缩实验对支架的组成、形貌、无机物沉积量、孔隙率以及压缩强度进行了表征.研究表明,处理后支架孔隙表面沉积了低结晶度的羟基磷灰石,低倍下沉积层均匀致密,在高的放大倍数下发现,沉积层中存在大量的微孔,沉积层表面存在着球状物,该球状物是由许多小片组成的.沉积6 h时沉积量为支架质量的2.81%,支架孔隙率由96.0%减少到89.8%.与纯壳聚糖支架相比,复合支架的压缩强度由0.0550 MPa提高到0.0998 MPa.
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| 关 键 词： | 壳聚糖 多孔支架 电化学辅助沉积 羟基磷灰石 涂层 |
| 收稿时间： | 2008-07-18 |
ELECTROCHEMISTRY ASSISTED DEPOSITING HYDROXYAPATITE COATING IN CHITOSAN POROUS SCAFFOLD |
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| HUANG Zhihai,LI Jihong,LIN Pinghua,DONG Yinsheng,GUO Chao,SHENG Xiaobo,CHU Chenglin.ELECTROCHEMISTRY ASSISTED DEPOSITING HYDROXYAPATITE COATING IN CHITOSAN POROUS SCAFFOLD[J].Acta Polymerica Sinica,2009,0(3):273-277. |
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| Authors: | HUANG Zhihai LI Jihong LIN Pinghua DONG Yinsheng GUO Chao SHENG Xiaobo CHU Chenglin |
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| Institution: | 1;2;~1 School of Materials Science and Engineering;Southeast University;Nanjing 211189;~2 School of Materials Science and Engineering;Hohai University;Nanjing 210098 |
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| Abstract: | Natural biopolymer chitosan has been investigated widely for a variety of biomedical applications due to its excellent biocompatibility and biodegradability.The toughness of chitosan porous scaffolds is good,but the strength is low.It is suggested that the coating treatment of hydroxyapatite will improve the strength and osteo-conductivity of the scaffolds,and maintain the toughness still.In this research,the electrochemistry assisted deposition method was used to deposit hydroxyapatite on the pores' surfac... |
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| Keywords: | Chitosan Porous scaffold Electrochemistry assisted deposition Hydroxyapatite Coating |
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