A rigid lanthanide binding tag for NMR structural analysis of carbohydrates |
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| Authors: | Mallagaray Alvaro Canales Angeles Domínguez Gema Jiménez-Barbero Jesús Pérez-Castells Javier |
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| Institution: | Facultad de Farmacia, Dpto. Química, Universidad San Pablo CEU, Urb. Montepríncipe, ctra. Boadilla km 5, 300 Boadilla del Monte, 28668 Madrid, Spain. |
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| Abstract: | The first synthesis of a carbohydrate molecule covalently bound to a rigid lanthanide binding tag is reported. This derivative has been designed as a new tool to provide long-range restraints for structural elucidation and molecular recognition studies of carbohydrates, thus extending the methodology already developed for proteins. |
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