Entirely green protocol for the synthesis of β-aminoketones using saccharose as a homogenous catalyst |
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Authors: | Mir Rasul Mousavi Nourallah Hazeri Malek Taher Maghsoodlou Sajjad Salahi Sayyed Mostafa Habibi-Khorassani |
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Institution: | Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674, Zahedan, Iran |
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Abstract: | Saccharose was applied as an efficient and homogenous catalyst for a one-pot, three-component Mannich reaction for the formation of β-aminoketones from aromatic aldehydes, anilines, and acetophenone at ambient temperature in excellent yields. This protocol has the following advantages: mild conditions, high yields, clean reaction profiles, operational simplicity, and environmentally benign and simple work-up procedures. |
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Keywords: | Saccharose &beta -Amino carbonyl compounds Mannich reaction Three-component reaction |
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