A new pyrrole alkaloid from Selaginella moellendorfii Hieron |
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| Authors: | Zhen-Xing Zou Kang-Ping Xu Fu-Shuang Li Hui Zou Min-Zhen Liu Qiong Zhang Kai Yu Lan-Fang Zhao Lei-Hong Tan Gui-Shan Tan |
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| Affiliation: | a School of Pharmaceutical Sciences, Central South University, Changsha 410013, China;b Xiangya Hospital of Central South University, Changsha 410008, China |
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| Abstract: | One new pyrrole alkaloid, N-(2E)-3-(3,4-dihydrophenyl)prop-N1'-(4-aminobutyl)-3-pyrrole formaldehyde (1), was isolated from the whole herbs of Selaginella moellendorfii Hieron. The structure was elucidated by spectroscopic analyses including UV, IR, 1D NMR, 2D NMR and MS methods. Additionally, compound 1 exhibited potent protective effect against the injury of human umbilical vein endothelial cell (HUVECs) induced by high concentrations of glucose in vitro. |
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| Keywords: | Selaginella Selaginella moellendorfii Hieron Pyrrole alkaloid HUVECs |
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