| 小剂量HpD配合可变脉宽532nm激光治疗鲜红斑痣的病理电镜研究 |
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| 引用本文： | 朱菁,秦梅香,张慧国,包晓青,周琳,施虹敏,张美珏,聂凡,袁霞雯.小剂量HpD配合可变脉宽532nm激光治疗鲜红斑痣的病理电镜研究[J].应用激光,2002,22(6):573-576. |
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| 作者姓名： | 朱菁 秦梅香 张慧国 包晓青 周琳 施虹敏 张美珏 聂凡 袁霞雯 |
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| 作者单位： | 上海第二医科大学附属仁济医院,上海市激光医学研究中心,上海,200001 |
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| 基金项目： | 上海市科技发展基金项目资助 项目编号 9941 1 90 61 |
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| 摘 要： | 目的 :寻求治疗鲜红斑痣疗效佳、对正常皮肤损伤小、副反应小的方法。方法 :以不同剂量HpD配合不同剂量带同步冷却装置的可变脉宽 5 3 2nm激光照射鲜红斑痣动物模型来克享大公鸡鸡冠 ,在不同时间进行组织病理和超微结构的研究。结果 :治疗后即刻血管内皮细胞肿胀明显导致管腔闭塞 ,腔内见破坏的红细胞碎片 ,反应较单纯激光治疗组严重。结论 :小剂量HpD配合可变脉宽 5 3 2nm激光治疗鲜红斑痣可以提高疗效
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| 关 键 词： | 鲜红斑痣 HpD 激光 |
| 收稿时间： | 2002/7/1 |
| 修稿时间： | 2002年7月1日 |
Light and Electron Microscopic Analysis of Port-Wine Stain Treated bySmall Dose HpD and Variable Pulsed 532nm Laser |
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| Zhu Jing,Qin Meixiang,Zhang Huiguo,et al.Light and Electron Microscopic Analysis of Port-Wine Stain Treated bySmall Dose HpD and Variable Pulsed 532nm Laser[J].Applied Laser,2002,22(6):573-576. |
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| Authors: | Zhu Jing Qin Meixiang Zhang Huiguo |
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| Abstract: | Objective:To obtain a new therapy of port-wine stain (PWS) with good effect and few side effects.Methods:The Leghorn combs chosen as the model and treated with small dose HpD and variable pulsed 532nm laser were evaluated histologically and ultrastructurally at different time. Results: Biopsies taken immediately after treatment showed that the endothelial cells of the capillaries are markedlyswollen and occlude the vascular lumen with small fragments of destroyed erythrocytes seen intravascularly. Conclusion: The results provide evidence that small dose HpD and variable pulsed 532nm laser can increase the efficacy of treatment in PWS ? |
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| Keywords: | port-wine stain (PWS) HpD laser |
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