New quinoxalines with nitrogen functions in the side chain. Potential inhibitors of 5-HT3

Starting with benzofuroxane 1 , 2-ethoxy-carbonyl-3-methylquinoxaline 1,4-dioxide 7 is obtained. From this compound different amides 5a-q and amino esters 6a-c are obtained. From 2-amino-3-cyanoquinoxaline 1,4-dioxide 7 , new amidines 9 , 5,4-b]pyrimido 10 and 6,5-b]diazepinoquinoxalines 11 were prepared.