Fluxional additives: a second generation control in enantioselective catalysis |
| |
| Authors: | Sibi Mukund P Manyem Shankar Palencia Hector |
| |
| Affiliation: | Department of Chemistry and Molecular Biology, North Dakota State University, Fargo, North Dakota 58105, USA. Mukund.Sibi@ndsu.edu |
| |
| Abstract: | The concept of "fluxional additives", additives that can adopt enantiomeric conformations depending on the chiral information in the ligand, is demonstrated in enantioselective Diels-Alder and nitrone cycloaddition reactions. The additive design is modular, and diverse structures are accessible in three steps. Chiral Lewis acids from main group and transition metals show enhancements in enantioselectivity in the presence of these additives. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
