Cyclic sulfamidates as vehicles for the synthesis of substituted lactams |
| |
| Authors: | Bower John F Svenda Jakub Williams Andrew J Charmant Jonathan P H Lawrence Ron M Szeto Peter Gallagher Timothy |
| |
| Affiliation: | School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK. |
| |
| Abstract: | [reaction: see text] A structurally diverse series of mono- and disubstituted 1,2- and 1,3-cyclic sulfamidates react with stabilized enolates, including malonate and phosphonoacetate variants, to provide, after lactamization, substituted and alpha-functionalized pyrrolidinone and piperidinone derivatives. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
