A new level set model for cell image segmentation |
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Authors: | Ma Jing-Feng Hou Kai Bao Shang-Lian Chen Chun |
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Affiliation: | College of Computer Science and Technology, Zhejiang University, Hangzhou 310027, China; Beijing Key Lab of Medical Physics and Engineering, Peking University, Beijing 100871, China; Beijing Healthway Technology Limited Company, Beijing 100084, China |
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Abstract: | In this paper we first determine three phases of cell images: background, cytoplasm and nucleolus according to the general physical characteristics of cell images, and then develop a variational model, based on these characteristics, to segment nucleolus and cytoplasm from their relatively complicated backgrounds. In the meantime, the preprocessing obtained information of cell images using the OTSU algorithm is used to initialize the level set function in the model, which can speed up the segmentation and present satisfactory results in cell image processing. |
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Keywords: | cell image segmentation 3-phase level set OTSU algorithm |
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